Lipidome Juxtaposition (LUX score)
LUX score is the first metric for comparing lipidomes. It provides a measure of homology between lipidomes similar to genetic analyses (Marella et al. 2015, PLOS Comp. Biol).
This application provides a form-based, web-based graphical user inteface to run LUX score.
LUX score related publications
- Dominik Schwudke, Andrej Shevchenko, Nils Hoffmann and Robert Ahrends, Lipidomics Informatics for Life-Science, Journal of Biotechnology, J Biotechnol. 261:131-136, 2017.
- Lars F. Eggers, Julia Müller, Chakravarthy Marella, Verena Scholz, Henrik Watz, Christian Kugler, Klaus F. Rabe, Torsten Goldmann & Dominik Schwudke, Lipidomes of lung cancer and tumour-free lung tissues reveal distinct molecular signatures for cancer differentiation, age, inflammation, and pulmonary emphysema, Scientific Reports, Sci Rep. 7(1):11087, 2017.
- Chakravarthy Marella, Andrew E. Torda and Dominik Schwudke, The LUX score: a metric for lipidome homology, PLoS computational biology, PLoS Comput Biol. 11(9):e1004511, 2015.